Buttigieg would be the first Senate-confirmed LGBTQ Cabinet secretary should his nomination make it through the chamber.
The choice vaults a candidate Biden spoke glowingly of after the Democratic primary into a top job in the incoming administration and could earn Buttigieg what many Democrats believe is needed experience should he run for president again.
The role of transportation secretary is expected to play a central role in Biden’s push for a bipartisan infrastructure package.
Buttigieg is seen as a rising star in the Democratic Party but someone who lacked an obvious path to higher elected office given the continued rightward shift of his home state of Indiana.